Ben Stiller

Larry Daley

(Acting)

Amy Adams

Amelia Earhart

(Acting)

Owen Wilson

Jedediah Smith

(Acting)

Hank Azaria

Kahmunrah / The Thinker / Abe Lincoln

(Acting)

Robin Williams

Theodore Roosevelt

(Acting)

Christopher Guest

Ivan the Terrible

(Acting)

Alain Chabat

Napoleon Bonaparte

(Acting)

Steve Coogan

Octavius

(Acting)

Ricky Gervais

Dr. McPhee

(Acting)

Bill Hader

George Armstrong Custer

(Acting)

Jon Bernthal

Al Capone

(Acting)

Patrick Gallagher

Attila the Hun

(Acting)

Jake Cherry

Nicky Daley

(Acting)

Rami Malek

Ahkmenrah

(Acting)

Mizuo Peck

Sacajawea

(Acting)

Kerry van der Griend

Neanderthal #1

(Acting)

Matthew Harrison

Neanderthal #2

(Acting)

Rick Dobran

Neanderthal #3

(Acting)

Randy Lee

Hun #1

(Acting)

Darryl Quon

Hun #2

(Acting)

Gerald Wong

Hun #3

(Acting)

Paul Chih-Ping Cheng

Hun #4

(Acting)

Jay Baruchel

Sailor Joey Motorola

(Acting)

Mindy Kaling

Docent

(Acting)

Keith Powell

Tuskegee Airman #1

(Acting)

Craig Robinson

Tuskegee Airman #2

(Acting)

Samuel Patrick Chu

Teenage Boy #1

(Acting)

Augustus Oicle

Teenage Boy #2

(Acting)

Kai James

Teenage Boy #3

(Acting)

Clint Howard

Air and Space Mission Control Tech #1

(Acting)

Matty Finochio

Air and Space Mission Control Tech #2

(Acting)

George Foreman

George Foreman

(Acting)

Josh Byer

Capone Gangster #1

(Acting)

Sophie Levy

Young Girl #1

(Acting)

Tess Levy

Young Girl #2

(Acting)

Christina Schild

'American Gothic' Woman

(Acting)

Robert Thurston

'American Gothic' Farmer

(Acting)

Alberta Mayne

Kissing Nurse

(Acting)

Clifton MaCabe Murray

Kissing Sailor

(Acting)

Caroll Spinney

Oscar the Grouch (voice)

(Acting)

Thomas Morley

Darth Vader

(Acting)

Dan Joffre

Town Car Driver

(Acting)

Dave Hospes

Astronaut

(Acting)

Regina Taufen

New York Reporter

(Acting)

Shawn Levy

Infomercial Father

(Production)

Joe Jonas

Cherub #1 (voice)

(Acting)

Kevin Jonas

Cherub #2 (voice)

(Acting)

Nick Jonas

Cherub #3 (voice)

(Acting)

Eugene Levy

Albert Einstein's (voice)

(Acting)

Brad Garrett

Easter Island Head (voice)

(Acting)

Ed Helms

Larry Daley's Assistant (uncredited)

(Acting)

Jonah Hill

Brundon the Security Guard (uncredited)

(Acting)

Thomas Lennon

Wilbur Wright (uncredited)

(Acting)

Crystal the Monkey

Dexter / Able (uncredited)

(Acting)